● 辦 公 室：醫學二館208

● 聯絡電話：(02) 2826-7000 #67981

● E-mail：chuangy@nycu.edu.tw

● 公衛所英文主頁 連結

● 學歷

○ 約翰霍普金斯大學(Johns Hopkins University)

○ 公共衛生精神健康學系博士(2012)

○ 台大 醫學系(2002)

● 經歷

○ 亞東醫院精神科主治醫師(2015-迄今)

○ 美國國家老化研究院(National Institute on Aging)博士後研究員(2012-2014)

○ 敏盛醫院精神科主治醫師(2007-2008)

○ 臺大醫院精神科住院醫師(2003-2007)

● 專長領域

精神疾病流行病學、老人認知、老人精神健康、老人藥物流行病學

● 研究興趣

老人認知功能退化及失智症危險因子及生物標誌、腦結構及功能性影像、

心血管疾病與老人失智、肥胖與老人失智

●代表著作 (6 篇)

1. Chuang, YF & Liu, YC & Tseng, HY & Lin, PX & Li, CY & Shih, MH & Lin, KC & Yang, TYO & Yan, SH & Chiu, YL. (2021).Urban-rural differences in the prevalence and correlates of mild cognitive impairment in community-dwelling older adults in Taiwan: The EMCIT study. Journal of the Formosan Medical Association. 120. 10.1016/j.jfma.2021.03.005.
2. Chiu, Y. L., Tsai, H. H., Lai, Y. J., Tseng, H. Y., Wu, Y. W., Peng, Y. Sen, … Chuang, Y. F. (2019). Cognitive impairment in patients with end-stage renal disease: Accelerated brain aging? Journal of the Formosan Medical Association. (in press) ttps://doi.org/10.1016/j.jfma.2019.01.011
3. Chuang YF, Elango P, Gonzalez CE, Thambisetty M. Midlife anticholinergic drug use, risk of Alzheimer’s disease, and brain atrophy in community-dwelling older adults. Alzheimer’s & Dementia: Translational Research & Clinical Interventions. 2017(3) 471-479
4. Chuang YF, Yang An, Murat Bilgel, Dean F. Wong, Juan C. Troncoso, Richard J. O’Brian, Luigi Ferruci, Susan M. Resnick, Madhav Thambisetty. Midlife Adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation. Mol Psychiatry. 2016 Jul;21(7):910-5
5. Chuang YF, Tanaka T, Beason-Held LL, An Y, Terracciano A, Sutin AR, Kraut M, Singleton AB, Resnick SM, Thambisetty M. FTO genotype and Aging: pleotrophic longitudinal effects on adiposity, brain function, impulsivity and food preference. Molecular Psychiatry 2015 Feb;20(1):140-7
6. Chuang YF, Breitner JC, Chiu YL, Khachaturian A, Hayden K, Corcoran C, Tschanz J, Norton M, Munger R, Welsh-Bohmer K, Zandi PP; For the Cache County Investigators. Use of diuretics is associated with reduced risk of Alzheimer’s disease: The Cache County Study. Neurobiology of aging 2014 Nov;35(11):2429-35

●公衛所指導學生論文 (代表 5 篇)

1. 睡眠品質對於認知功能表現以及大腦結構改變在台灣老年族群相關性之探討
2. 探討社區老人心血管危險因子負擔與認知功能改變之相關性
3. 台灣中老年人社交活動參與對認知功能的影響探討
4. 台灣老年族群暴露於空氣及噪音汙染對認知功能表現相關性之探討
5. 主觀睡眠品質對於認知功能表現與大腦結構和白質完整性 在台灣社區老年族群關聯性之探討